Gamma oryzanol, derived from rice bran, has been extensively researched in Japan for its healing effects in the treatment of gastric and duodenal ulcers. It has potent antioxidant activity and a supply of Ferulic acid (Rep Hokaido Inst Pub Health, 1966; 16: 111). These studies have found that Ferulic acid appears to enhance the activity of the parasympathetic nervous system and to promote endorphin release by the hypothalamus - actions which may regulate blood vessel tone and influence hormonal release patterns. Gamma oryzanol is also believed to be effective in the treatment of a broad range of gastrointestinal disorders including stress-induced gastric and duodenal ulcers, gastritis, irritable bowel syndrome, and non-specific gastrointestinal complaints.